I have stayed at several hotels over my years at otakons past. I will give you my reviews of the past two.
Place I stayed: Holiday Inn - Inner Harbor
Number of People in room: 1 (2008-2007), 5(2006),7(2005)
Hotel Staff: Great in recent years, in 2006 I had an incident with the night staff but the day time manager upgraded me to a suite because of major problems with my room.
Walk to the con center: At most 5-10 minutes depending on the trolleys and traffic crossing the street.
The bad: TV front hook-ups are disabled. Parking was 21 dollars a night, 19 if you are a priority club