Thinking on this today; I realized that barring another major spike that could trigger a new lock down, it's almost a certainty that Otakon will take place this summer. With no state of emergency the convention is locked into its contractual obligations and would have to pay for the convention center regardless of whether or not they use it.
Hopefully the trends continue positive, the fans show up, (and Otakon pinches a few extra pennies just to be safe).